Clear Search sequence regions


Sizes of these terms reflect their relevance to your search.

Cardiovascular disease, a leading cause of death worldwide, is frequently initiated or exacerbated by stress. In fact, chronic stress exposure and heightened reactions to acute psychological stress are both associated with increased cardiovascular morbidity. This brief review focuses on the mechanisms by which corticolimbic nuclei, critical for stress appraisal and emotional reactivity, regulate heart rate and blood pressure responses to psychological stress. Both human and rodent data are examined with a major emphasis on basic studies investigating prefrontal cortex, amygdala, and hippocampus. A detailed literature review reveals substantial limitations in our understanding of this circuitry, as well as significant opportunities for future investigation that may ultimately reduce the burden of cardiovascular illness. Copyright © 2016 Elsevier Inc. All rights reserved.

Citation

Brent Myers. Corticolimbic regulation of cardiovascular responses to stress. Physiology & behavior. 2017 Apr 01;172:49-59

Expand section icon Mesh Tags


PMID: 27793557

View Full Text