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QuickView for CYP1A1 (gene)


Gene Symbol:
CYP1A1 Homo sapiens Homo sapiens
Full name:
cytochrome P450, family 1, subfamily A, polypeptide 1
Synonyms:
P450-C, P450DX, P1-450, OTTHUMP00000183469, cytochrome P1-450, dioxin-inducible, cytochrome P450 1A1, cytochrome P450 form 6, cytochrome P450, family 1, subfamily A, polypeptide 1, cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1, cytochrome P450-C, cytochrome P450-P1, CYP1, CYPIA1, AHH, AHRR, CP11, aryl hydrocarbon hydroxylase, xenobiotic monooxygenase, flavoprotein-linked monooxygenase
Genomic Location:
Chr 15: 72798943-72804930
Description:
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aro...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: miRecords):
Cytogenetic Map:
chr 15
15q24.1


Transcripts Names
NM_000499
Protein Names
P04798
A0N0X8
Q53G18



GO Molecular Function

vitamin D 24-hydroxylase activity | cation binding | iron ion binding | binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | electron carrier activity | ion binding | organic cyclic compound binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | tetrapyrrole binding | oxygen binding | transition metal ion binding | heme binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity | aromatase activity

GO Biological Process

vitamin D 24-hydroxylase activity | cellular process | cellular response to chemical stimulus | xenobiotic metabolic process | organic cyclic compound metabolic process | cellular lipid metabolic process | response to stimulus | response to chemical stimulus | cellular response to xenobiotic stimulus | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | lipid metabolic process | fat-soluble vitamin metabolic process | small molecule metabolic process | response to xenobiotic stimulus | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | drug metabolic process | vitamin metabolic process | metabolic process | primary metabolic process | oxidation-reduction process | cellular response to stimulus | organic substance metabolic process | steroid metabolic process | cellular metabolic process | oxidoreductase activity | aromatase activity | vitamin D metabolic process

GO Cellular Component

endoplasmic reticulum part | intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | organelle part | intracellular organelle part | membrane part | cell part | membrane-bounded organelle | organelle | cytoplasmic part | intracellular part | intracellular | membrane