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QuickView for CYP2A6 (gene)


Gene Symbol:
CYP2A6 Homo sapiens Homo sapiens
Full name:
cytochrome P450, family 2, subfamily A, polypeptide 6
Synonyms:
cytochrome P450 2A6, cytochrome P450 IIA3, cytochrome P450(I), cytochrome P450, family 2, subfamily A, polypeptide 6, cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 6, CYP2A, CYP2A3, CYPIIA6, coumarin 7-hydroxylase, CPA6, P450C2A, P450PB, xenobiotic monooxygenase, flavoprotein-linked monooxygenase
Genomic Location:
Chr 19: 46041284-46048180
Description:
This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The ...
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 19
19q13.2





GO Molecular Function

coumarin 7-hydroxylase activity | cation binding | enzyme binding | iron ion binding | binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | electron carrier activity | ion binding | organic cyclic compound binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | tetrapyrrole binding | protein binding | transition metal ion binding | heme binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity

GO Biological Process

molting cycle | coumarin 7-hydroxylase activity | response to drug | cellular process | exogen | cellular response to chemical stimulus | tissue development | phenylpropanoid metabolic process | xenobiotic metabolic process | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | response to stimulus | response to chemical stimulus | cellular response to xenobiotic stimulus | heterocycle catabolic process | coumarin catabolic process | hair follicle maturation | cellular catabolic process | drug catabolic process | catalytic activity | system development | multicellular organismal development | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | lipid metabolic process | single-organism process | small molecule metabolic process | exogenous drug catabolic process | epidermis development | response to xenobiotic stimulus | molting cycle process | aromatic compound catabolic process | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | anatomical structure maturation | organic cyclic compound catabolic process | drug metabolic process | hair cycle | anatomical structure development | metabolic process | primary metabolic process | developmental maturation | oxidation-reduction process | phenylpropanoid catabolic process | hair cycle process | cellular response to stimulus | organic substance metabolic process | organ development | secondary metabolic process | steroid metabolic process | coumarin metabolic process | developmental process | single-multicellular organism process | heterocycle metabolic process | cellular metabolic process | oxidoreductase activity | hair follicle development | multicellular organismal process

GO Cellular Component

endoplasmic reticulum part | intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | organelle part | intracellular organelle part | membrane part | cell part | membrane-bounded organelle | organelle | cytoplasmic part | intracellular part | intracellular | membrane