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QuickView for CYP2B6 (gene)


Gene Symbol:
CYP2B6 Homo sapiens Homo sapiens
Full name:
cytochrome P450, family 2, subfamily B, polypeptide 6
Synonyms:
CYP2B, CYP2B7, CYP2B7P, CYPIIB6, cytochrome P450 2B6, cytochrome P450 IIB1, cytochrome P450, family 2, subfamily B, polypeptide 6, cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6, EFVM, CPB6, P450, IIB1
Genomic Location:
Chr 19: 46189044-46216141
Description:
This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The ...
Orthologs:
Mus musculus Rattus norvegicus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 19
19q13.2


Transcripts Names
NM_000767
Protein Names
Q9UK46
P20813
Q2V565



GO Molecular Function

cation binding | iron ion binding | binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | electron carrier activity | ion binding | organic cyclic compound binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | tetrapyrrole binding | transition metal ion binding | heme binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity

GO Biological Process

molting cycle | response to drug | cellular process | exogen | cellular response to chemical stimulus | tissue development | xenobiotic metabolic process | catabolic process | organic cyclic compound metabolic process | response to stimulus | response to chemical stimulus | cellular response to xenobiotic stimulus | hair follicle maturation | cellular catabolic process | drug catabolic process | catalytic activity | system development | multicellular organismal development | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | lipid metabolic process | single-organism process | small molecule metabolic process | exogenous drug catabolic process | cellular ketone metabolic process | epidermis development | response to xenobiotic stimulus | molting cycle process | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | anatomical structure maturation | drug metabolic process | hair cycle | anatomical structure development | metabolic process | primary metabolic process | developmental maturation | oxidation-reduction process | hair cycle process | cellular response to stimulus | organic substance metabolic process | organ development | steroid metabolic process | developmental process | single-multicellular organism process | cellular metabolic process | oxidoreductase activity | hair follicle development | multicellular organismal process

GO Cellular Component

endoplasmic reticulum part | intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | organelle part | intracellular organelle part | membrane part | cell part | membrane-bounded organelle | organelle | cytoplasmic part | intracellular part | intracellular | membrane