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QuickView for CYP4A11 (gene)


Gene Symbol:
CYP4A11 Homo sapiens Homo sapiens
Full name:
cytochrome P450, family 4, subfamily A, polypeptide 11
Synonyms:
CYP4A2, CYP4AII, CYPIVA11, cytochrome P-450HK-omega, cytochrome P450 4A11, cytochrome P450, family 4, subfamily A, polypeptide 11, cytochrome P450, subfamily IVA, polypeptide 11, cytochrome P450HL-omega, CP4Y, 20-HETE synthase, 20-hydroxyeicosatetraenoic acid synthase, alkane-1 monooxygenase, P450HL-omega, OTTHUMP00000009714, fatty acid omega-hydroxylase, lauric acid omega-hydroxylase
Genomic Location:
Chr 1: 47167433-47180004
Description:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Danio rerio
External Links:
Entrez Gene
Cytogenetic Map:
chr 1
1p33


Transcripts Names
NM_000778



GO Molecular Function

arachidonic acid omega-hydroxylase activity | cation binding | iron ion binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen | binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | electron carrier activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen | ion binding | organic cyclic compound binding | arachidonic acid monooxygenase activity | tetrapyrrole binding | transition metal ion binding | alkane 1-monooxygenase activity | heme binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity | leukotriene-B4 20-monooxygenase activity | arachidonic acid epoxygenase activity

GO Biological Process

regulation of biological process | leukotriene metabolic process | regulation of localization | regulation of biological quality | renal water homeostasis | arachidonic acid omega-hydroxylase activity | regulation of lipid transport | cellular process | cellular response to chemical stimulus | regulation of organic acid transport | xenobiotic metabolic process | catabolic process | cellular lipid metabolic process | response to stimulus | oxoacid metabolic process | monocarboxylic acid metabolic process | response to chemical stimulus | cellular response to xenobiotic stimulus | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen | blood circulation | cellular catabolic process | catalytic activity | metal ion homeostasis | renal system process involved in regulation of blood volume | water homeostasis | sodium ion homeostasis | positive regulation of icosanoid secretion | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | lipid metabolic process | positive regulation of secretion | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen | regulation of blood pressure | regulation of systemic arterial blood pressure | cellular alkene metabolic process | pressure natriuresis | single-organism process | small molecule metabolic process | leukotriene B4 catabolic process | biological regulation | cellular ketone metabolic process | unsaturated fatty acid metabolic process | response to xenobiotic stimulus | cation homeostasis | positive regulation of biological process | regulation of icosanoid secretion | system process | homeostatic process | positive regulation of transport | long-chain fatty acid metabolic process | arachidonic acid monooxygenase activity | carboxylic acid metabolic process | metabolic process | primary metabolic process | circulatory system process | regulation of body fluid levels | oxidation-reduction process | chemical homeostasis | regulation of secretion | olefin metabolic process | cellular response to stimulus | organic substance metabolic process | ion homeostasis | alkene catabolic process | renal system process | fatty acid metabolic process | monovalent inorganic cation homeostasis | positive regulation of organic acid transport | icosanoid metabolic process | alkane 1-monooxygenase activity | organic acid metabolic process | epoxygenase P450 pathway | renal system process involved in regulation of systemic arterial blood pressure | leukotriene catabolic process | regulation of transport | regulation of fatty acid transport | multicellular organismal water homeostasis | leukotriene B4 metabolic process | single-multicellular organism process | positive regulation of lipid transport | cellular metabolic process | oxidoreductase activity | arachidonic acid metabolic process | leukotriene-B4 20-monooxygenase activity | arachidonic acid epoxygenase activity | positive regulation of fatty acid transport | multicellular organismal process

GO Cellular Component

endoplasmic reticulum part | intracellular membrane-bounded organelle | plasma membrane part | apical plasma membrane | organelle membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | apical part of cell | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | plasma membrane | organelle part | intracellular organelle part | membrane part | cell part | membrane-bounded organelle | organelle | cell periphery | cytoplasmic part | intracellular part | intracellular | membrane