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QuickView for CYP51 (gene)


Gene Symbol:
Cyp51 Rattus norvegicus Rattus norvegicus
Full name:
cytochrome P450, family 51
Synonyms:
P450-14DM, P45014DM, P450LI, MGC93630, RATCP14DM, sterol 14-alpha demethylase, lanosterol 14-alpha demethylase, Ldm, Cytochrom P450 Lanosterol 14 alpha-demethylase, cytochrome P450 51A1, cytochrome P450 Lanosterol 14 alpha-demethylase, cytochrome P450, family 51, cytochrome P450, family 51, subfamily A, polypeptide 1, cytochrome P450, subfamily 51, cytochrome P450-14DM, cytochrome P45014DM, cytochrome P450LI, Cyp51a1, CYPLI
Genomic Location:
Chr 4: 26752677-26771131
Description:
gene amplification is detected in some endometrial carcinomas [RGD]
Orthologs:
Homo sapiens Mus musculus Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
NM_012941
Protein Names
Q64549
Q64654



GO Molecular Function

sterol 14-demethylase activity | cation binding | iron ion binding | demethylase activity | binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | electron carrier activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen | ion binding | organic cyclic compound binding | tetrapyrrole binding | transition metal ion binding | heme binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity

GO Biological Process

regulation of biological process | regulation of biosynthetic process | organic cyclic compound biosynthetic process | sterol 14-demethylase activity | sterol metabolic process | regulation of metabolic process | organic cyclic compound metabolic process | steroid biosynthetic process | demethylase activity | alcohol metabolic process | regulation of steroid biosynthetic process | regulation of steroid metabolic process | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | lipid metabolic process | regulation of cholesterol biosynthetic process | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen | sterol biosynthetic process | small molecule metabolic process | regulation of cholesterol metabolic process | biological regulation | biosynthetic process | regulation of primary metabolic process | cholesterol biosynthetic process | lipid biosynthetic process | regulation of lipid biosynthetic process | metabolic process | primary metabolic process | cholesterol metabolic process | oxidation-reduction process | cholesterol biosynthetic process via 24,25-dihydrolanosterol | organic substance metabolic process | steroid metabolic process | demethylation | regulation of lipid metabolic process | oxidoreductase activity

GO Cellular Component

endoplasmic reticulum part | integral to membrane | intracellular membrane-bounded organelle | organelle membrane | cell | intrinsic to membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | organelle part | intracellular organelle part | membrane part | cell part | membrane-bounded organelle | organelle | cytoplasmic part | intracellular part | intracellular | membrane