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QuickView for TPO-2 (gene)


Gene Symbol:
THPO Homo sapiens Homo sapiens
Full name:
thrombopoietin
Synonyms:
TPO, THCYT1, thrombopoietin, thrombopoietin nirs variant 1, c-mpl ligand, megakaryocyte colony-stimulating factor, megakaryocyte growth and development factor, megakaryocyte stimulating factor, MGC163194, MPL ligand, MPLLG, MKCSF, ML, MGDF, myeloproliferative leukemia virus oncogene ligand
Genomic Location:
Chr 3: 185572467-185578626
Description:
Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. ...
Orthologs:
Mus musculus Rattus norvegicus Gallus gallus Bos taurus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Unknown transcription factor binding site geneset 13 Unknown transcription factor binding site geneset 14 CUTL1 binding site geneset 1 Unknown transcription factor binding site geneset 40 EGR2 binding site geneset 1 Unknown transcription factor binding site geneset 56 Unknown transcription factor binding site geneset 65 PPARA binding site geneset 3 PITX2 binding site geneset 3 Unknown transcription factor binding site geneset 91
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 3
3q27