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QuickView for Vitamin B 2 (compound)


PubChem
Name: Riboflavin
PubChem Compound ID: 1072
Description: Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as FLAVIN MONONUCLEOTIDE and FLAVIN-ADENINE DINUCLEOTIDE.
Molecular formula: C17H20N4O6
Molecular weight: 376.364 g/mol
Synonyms:
Vitamin B2; 83-88-5; Benzo[g]pteridine-2,4(3H,10H)-dione, 7,8-dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)-; Hyflavin; Lyxoflavine; Flaxain; 6,7-Dimethyl-9-D-ribitylisoalloxazine; Riboflavin; Vitamin Bi; Ribotone.
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DrugBank
Identification
Name: Riboflavin
Name (isomeric): DB00140
Drug Type: small molecule
Description: Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as FLAVIN MONONUCLEOTIDE and FLAVIN-ADENINE DINUCLEOTIDE.
Synonyms:
Riboflavine [INN-French]; Lactoflavin; Vitamin B2; Riboflavina [INN-Spanish]; Lactoflavine; Vitamin Bi; Vitamin G; Russupteridine Yellow III; Riboflavinum [INN-Latin]
Brand: Hyflavin, Dermadram, Beflavine, Hyre, Ribovel, Flaxain, Ribocrisina, Vitasan B2, Riboderm, Ribosyn, Fiboflavin, Ovoflavin, Lactobene, HSDB 817, Flavin Bb, Vitaflavine, Ribotone, Flavin, Bisulase, Beflavin, Flavaxin, Ribipca, Aqua-Flave
Category: Photosensitizing Agents, Vitamin B Complex, Radiation-Sensitizing Agents, Vitamins (Vitamin B Complex)
CAS number: 83-88-5
Pharmacology
Indication: For the treatment of ariboflavinosis (vitamin B2 deficiency).
Pharmacology:
Riboflavin or vitamin B2 is an easily absorbed, water-soluble micronutrient with a key role in maintaining human health. Like the other B vitamins, it supports energy production by aiding in the metabolising of fats, carbohydrates, and proteins. Vitamin B2 is also required for red blood cell formation and respiration, antibody production, and for r...
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Mechanism of Action:
Binds to riboflavin hydrogenase, riboflavin kinase, and riboflavin synthase. Riboflavin is the precursor of flavin mononucleotide (FMN, riboflavin monophosphate) and flavin adenine dinucleotide (FAD). The antioxidant activity of riboflavin is principally derived from its role as a precursor of FAD and the role of this cofactor in the production of ...
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Absorption: Vitamin B2 is readily absorbed from the upper gastrointestinal tract.
Protein binding: 60%
Biotransformation: Hepatic.
Half Life: 66-84 minutes
Affected organisms: Humans and other mammals

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