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PubChem
Name: Biotin
PubChem Compound ID: 10444559
Description: A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
Molecular formula: C10H16N2O3S
Molecular weight: 245.305 g/mol
DrugBank
Identification
Name: Biotin
Name (isomeric): DB00121
Drug Type: small molecule
Description: A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
Synonyms:
D(+)-Biotin; cis-(+)-Tetrahydro-2-oxothieno[3,4]imidazoline-4-valeric acid; (+)-Biotin; Vitamin H; (+)-cis-Hexahydro-2-oxo-1H-thieno[3,4]imidazole-4-valeric acid; Coenzyme R; D-Biotin; Vitamin B7
Brand: Bios II, Meribin, Lutavit H2, Biodermatin, Factor S, Bioepiderm, Biotin Forte, Rovimix H2
Category: Micronutrient, Vitamin B Complex, Dietary supplement, Vitamins (Vitamin B Complex)
CAS number: 58-85-5
Pharmacology
Indication: For nutritional supplementation, also for treating dietary shortage or imbalance.
Pharmacology:
Biotin is a water-soluble B-complex vitamin which is composed of an ureido ring fused with a tetrahydrothiophene ring. A valeric acid substituent is attached to one of the carbon atoms of the tetrahydrothiophene ring. Biotin is used in cell growth, the production of fatty acids, metabolism of fats, and amino acids. It plays a role in the Kreb cycle...
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Mechanism of Action: Biotin is necessary for the proper functioning of enzymes that transport carboxyl units and fix carbon dioxide, and is required for various metabolic functions, including gluconeogenesis, lipogenesis, fatty acid biosynthesis, propionate metabolism, and catabolism of branched-chain amino acids.
Absorption: Systemic - approximately 50%
Toxicity: Prolonged skin contact may cause irritation.
Affected organisms: Humans and other mammals

Targets


Enzymes